p38 MAP kinase modulates liver cell volume through inhibition of membrane Na(+) permeability

In hepatocytes, Na(+) influx through nonselective cation (NSC) channels represents a key point for regulation of cell volume. Under basal conditions, channels are closed, but both physiologic and pathologic stimuli lead to a large increase in Na(+) and water influx. Since osmotic stimuli also activa...

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Pubblicato in:	J Clin Invest
Autori principali:	Feranchak, Andrew P., Berl, Tomas, Capasso, Juan, Wojtaszek, Paul A., Han, Jiahuai, Fitz, J. Gregory
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11714741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12190
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