Anti-ganglioside antibodies alter presynaptic release and calcium influx

Acute motor axonal neuropathy (AMAN) variant of Guillain-Barré syndrome is often associated with IgG anti-GM1 and -GD1a antibodies. The pathophysiological basis of antibody-mediated selective motor nerve dysfunction remains unclear. We investigated the effects of IgG anti-GM1 and -GD1a monoclonal an...

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Main Authors: Buchwald, Brigitte, Zhang, Gang, Vogt-Eisele, Angela K., Zhang, Weiyi, Ahangari, Raheleh, Griffin, John W., Hatt, Hanns, Toyka, Klaus V., Sheikh, Kazim A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094038/
https://ncbi.nlm.nih.gov/pubmed/17720506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.07.008
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