Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease

Spinal cord injury results in a massive loss of neurons, and thus of function. We recently reported that passive transfer of autoimmune T cells directed against myelin-associated antigens provides acutely damaged spinal cords with effective neuroprotection. The therapeutic time window for the passiv...

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Main Authors: Hauben, Ehud, Agranov, Eugenia, Gothilf, Amalia, Nevo, Uri, Cohen, Avi, Smirnov, Igor, Steinman, Lawrence, Schwartz, Michal
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2001
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC209402/
https://ncbi.nlm.nih.gov/pubmed/11518733
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