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CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects

HIV-1–specific cytotoxic T-lymphocyte (CTL) responses have been detected at a low frequency in many HIV-1–exposed, persistently seronegative (HEPS) subjects. However, it is unclear how CTLs could protect against HIV acquisition in HEPS subjects, when high levels of circulating CTL fail to prevent di...

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Detalhes bibliográficos
Main Authors: Kaul, Rupert, Dong, Tao, Plummer, Francis A., Kimani, Joshua, Rostron, Timothy, Kiama, Peter, Njagi, Ephantus, Irungu, Erastus, Farah, Bashir, Oyugi, Julius, Chakraborty, Rana, MacDonald, Kelly S., Bwayo, Job J., McMichael, Andrew, Rowland-Jones, Sarah L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209302/
https://ncbi.nlm.nih.gov/pubmed/11375420
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