Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis

Dendritic cells (DCs) are specialized antigen-presenting cells that migrate from the periphery to lymphoid tissues, where they activate and regulate T cells. Genetic modification of DCs to express immunoregulatory molecules would provide a new immunotherapeutic strategy for autoimmune and other dise...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Morita, Yoshitaka, Yang, Jianmin, Gupta, Raj, Shimizu, Koichi, Shelden, Eric A., Endres, Judith, Mulé, James J., McDonagh, Kevin T., Fox, David A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 2001
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11375417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11490
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