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ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis

Matrix metalloproteinase-1 (MMP-1), or interstitial collagenase, has been hypothesized to contribute to the progression of the human atherosclerotic lesions by digesting the fibrillar collagens of the neointimal ECM. The apolipoprotein E knockout (apoE0) mouse model develops complex atherosclerotic...

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Autors principals: Lemaître, Vincent, O’Byrne, Timothy K., Borczuk, Alain C., Okada, Yasunori, Tall, Alan R., D’Armiento, Jeanine
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC209293/
https://ncbi.nlm.nih.gov/pubmed/11375412
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