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Automated high resolution optical mapping using arrayed, fluid-fixed DNA molecules
New mapping approaches construct ordered restriction maps from fluorescence microscope images of individual, endonuclease-digested DNA molecules. In optical mapping, molecules are elongated and fixed onto derivatized glass surfaces, preserving biochemical accessibility and fragment order after enzym...
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Prif Awduron: | , , , , , , , , , , , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
The National Academy of Sciences
1998
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20926/ https://ncbi.nlm.nih.gov/pubmed/9653137 |
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