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Effects of Genetic Mutations and Chemical Exposures on Caenorhabditis elegans Feeding: Evaluation of a Novel, High-Throughput Screening Assay

BACKGROUND: Government agencies have defined a need to reduce, refine or replace current mammalian-based bioassays with testing methods that use alternative species. Invertebrate species, such as Caenorhabditis elegans, provide an attractive option because of their short life cycles, inexpensive mai...

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Détails bibliographiques
Auteurs principaux: Boyd, Windy A., McBride, Sandra J., Freedman, Jonathan H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2092392/
https://ncbi.nlm.nih.gov/pubmed/18060055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001259
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