Cloning and expression of daunorubicin biosynthesis genes from Streptomyces peucetius and S. peucetius subsp. caesius.

Genes for the biosynthesis of daunorubicin (daunomycin) and doxorubicin (adriamycin), important antitumor drugs, were cloned from Streptomyces peucetius (the daunorubicin producer) and S. peucetius subsp. caesius (the doxorubicin producer) by use of the actI/tcmIa and actIII polyketide synthase gene...

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Détails bibliographiques

Publié dans:	J Bacteriol
Auteurs principaux:	Otten, S L, Stutzman-Engwall, K J, Hutchinson, C R
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209154/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2345153/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.6.3427-3434.1990
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