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Five independent combinations of mutations can result in low-affinity penicillin-binding protein 2x of Streptococcus pneumoniae.

Penicillin-binding protein 2x (PBP 2x) of Streptococcus pneumoniae is one of the high-molecular-weight PBPs involved in the development of intrinsic beta-lactam resistance. Point mutations in the PBP 2x genes (pbpX) have now been characterized in five independent spontaneous laboratory mutants in or...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Laible, G, Hakenbeck, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1938899/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.21.6986-6990.1991
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