Mutation and cloning of eryG, the structural gene for erythromycin O-methyltransferase from Saccharopolyspora erythraea, and expression of eryG in Escherichia coli.

A mutant strain derived by chemical mutagenesis of Saccharopolyspora erythraea (formerly known as Streptomyces erythreus) was isolated that accumulated erythromycin C and, to a lesser extent, its precursor, erythromycin D, with little or no production of erythromycin A or erythromycin B (the 3"-O-me...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Paulus, T J, Tuan, J S, Luebke, V E, Maine, G T, DeWitt, J P, Katz, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2185226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.5.2541-2546.1990
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