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IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease

BCR-ABL expression led to a dramatic up-regulation of the IL-3, IL-5, and granulocyte–macrophage colony-stimulating factor receptor β common (IL-3Rβc) and IL-3 receptor β (IL-3Rβ) chains in murine embryonic stem cell-derived hematopoietic cells coincident with an expansion of multipotent progenitors...

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Autores principales: Wong, Stephane, McLaughlin, Jami, Cheng, Donghui, Shannon, Kevin, Robb, Lorraine, Witte, Owen N.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC208809/
https://ncbi.nlm.nih.gov/pubmed/14500898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2035020100
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