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Conserved pathways within bacteria and yeast as revealed by global protein network alignment

We implement a strategy for aligning two protein–protein interaction networks that combines interaction topology and protein sequence similarity to identify conserved interaction pathways and complexes. Using this approach we show that the protein–protein interaction networks of two distantly relate...

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Autori principali: Kelley, Brian P., Sharan, Roded, Karp, Richard M., Sittler, Taylor, Root, David E., Stockwell, Brent R., Ideker, Trey
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC208768/
https://ncbi.nlm.nih.gov/pubmed/14504397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1534710100
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