Conserved pathways within bacteria and yeast as revealed by global protein network alignment

We implement a strategy for aligning two protein–protein interaction networks that combines interaction topology and protein sequence similarity to identify conserved interaction pathways and complexes. Using this approach we show that the protein–protein interaction networks of two distantly relate...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kelley, Brian P., Sharan, Roded, Karp, Richard M., Sittler, Taylor, Root, David E., Stockwell, Brent R., Ideker, Trey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14504397/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1534710100
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