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Positionally cloned human disease genes: Patterns of evolutionary conservation and functional motifs

Positional cloning has already produced the sequences of more than 70 human genes associated with specific diseases. In addition to their medical importance, these genes are of interest as a set of human genes isolated solely on the basis of the phenotypic effect of the respective mutations. We anal...

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Hlavní autoři: Mushegian, Arcady R., Bassett, Douglas E., Boguski, Mark S., Bork, Peer, Koonin, Eugene V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC20866/
https://ncbi.nlm.nih.gov/pubmed/9159160
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