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Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid

Retinoic acid is one of the most promising drugs for chemotherapy and chemoprevention of cancer. Either blocking activator protein-1 (AP-1) activity or activating retinoic acid response element (RARE) have been proposed to be responsible for its antitumor activity. However, evidence for this hypothe...

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Autori principali: Huang, Chuanshu, Ma, Wei-Ya, Dawson, Marcia I., Rincon, Mercedes, Flavell, Richard A., Dong, Zigang
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20865/
https://ncbi.nlm.nih.gov/pubmed/9159159
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