Identification of BlaR, the signal transducer for beta-lactamase production in Bacillus licheniformis, as a penicillin-binding protein with strong homology to the OXA-2 beta-lactamase (class D) of Salmonella typhimurium.

The blaR gene of Bacillus licheniformis encodes the signal transducer for induction of the class A beta-lactamase. The protein product, BlaR, has a hydrophilic carboxy region that binds beta-lactams and shows high sequence homology to the class D beta-lactamases, particularly the OXA-2 beta-lactamas...

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Pubblicato in:	J Bacteriol
Autori principali:	Zhu, Y F, Curran, I H, Joris, B, Ghuysen, J M, Lampen, J O
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2404938/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.2.1137-1141.1990
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