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Exploiting temperature-dependent substrate promiscuity for nucleoside analog activation by thymidine kinase from Thermotoga maritima

Enzymes from thermophilic and hyperthermophilic organisms are invaluable catalysts for organic synthesis and biotechnology due to their stability and function at elevated temperatures. While the temperature dependency of catalysis with normal substrates has been studied for several of these enzymes,...

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Detalhes bibliográficos
Main Authors: Lutz, Stefan, Lichter, Joseph, Liu, Lingfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2085358/
https://ncbi.nlm.nih.gov/pubmed/17592850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0734391
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