Functional analysis of the Shiga toxin and Shiga-like toxin type II variant binding subunits by using site-directed mutagenesis.

The B subunit of Shiga toxin and the Shiga-like toxins (SLTs) mediates receptor binding, cytotoxic specificity, and extracellular localization of the holotoxin. While the functional receptor for Shiga toxin, SLT type I (SLT-I), and SLT-II is the glycolipid designated Gb3, SLT-II variant (SLT-IIv) ma...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Jackson, M P, Wadolkowski, E A, Weinstein, D L, Holmes, R K, O'Brien, A D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2404947/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.2.653-658.1990
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