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Functional analysis of the Shiga toxin and Shiga-like toxin type II variant binding subunits by using site-directed mutagenesis.

The B subunit of Shiga toxin and the Shiga-like toxins (SLTs) mediates receptor binding, cytotoxic specificity, and extracellular localization of the holotoxin. While the functional receptor for Shiga toxin, SLT type I (SLT-I), and SLT-II is the glycolipid designated Gb3, SLT-II variant (SLT-IIv) ma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jackson, M P, Wadolkowski, E A, Weinstein, D L, Holmes, R K, O'Brien, A D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC208490/
https://ncbi.nlm.nih.gov/pubmed/2404947
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