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Independent signals regulate development of primary and secondary follicle structure in spleen and mesenteric lymph node

Lymphotoxin-α-deficient (LT-α(−/−)) mice manifest congenital absence of lymph nodes (LNs) and Peyer’s patches and disturbed spleen follicle structure. The splenic white pulp areas show loss of discrete T and B lymphocyte zones, of follicular dendritic cell (FDC) clusters, and of germinal centers (GC...

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Autori principali: Fu, Yang-Xin, Huang, Guangming, Matsumoto, Mitsuru, Molina, Hector, Chaplin, David D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20849/
https://ncbi.nlm.nih.gov/pubmed/9159143
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