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Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents
Dopamine (DA) released from the hypothalamus tonically inhibits pituitary lactotrophs. DA (at micromolar concentration) opens potassium channels, hyperpolarizing the lactotrophs and thus preventing the calcium influx that triggers prolactin hormone release. Surprisingly, at concentrations ~1000 lowe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084488/ https://ncbi.nlm.nih.gov/pubmed/17058022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10827-006-0008-4 |
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