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Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone

PPARγ regulates both glucose metabolism and bone mass. Recent evidence suggests that the therapeutic modulation of PPARγ activity with anti-diabetic thiazolidinediones elicits unwanted effects on bone. In this study, the effects of rosiglitazone on the skeleton of growing (1 month), adult (6 month),...

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Autors principals: Lazarenko, Oxana P., Rzonca, Sylwia O., Hogue, William R., Swain, Frances L., Suva, Larry J., Lecka-Czernik, Beata
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084459/
https://ncbi.nlm.nih.gov/pubmed/17332064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-1587
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