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Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone

PPARγ regulates both glucose metabolism and bone mass. Recent evidence suggests that the therapeutic modulation of PPARγ activity with anti-diabetic thiazolidinediones elicits unwanted effects on bone. In this study, the effects of rosiglitazone on the skeleton of growing (1 month), adult (6 month),...

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Detalhes bibliográficos
Main Authors: Lazarenko, Oxana P., Rzonca, Sylwia O., Hogue, William R., Swain, Frances L., Suva, Larry J., Lecka-Czernik, Beata
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084459/
https://ncbi.nlm.nih.gov/pubmed/17332064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-1587
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