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Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone

PPARγ regulates both glucose metabolism and bone mass. Recent evidence suggests that the therapeutic modulation of PPARγ activity with anti-diabetic thiazolidinediones elicits unwanted effects on bone. In this study, the effects of rosiglitazone on the skeleton of growing (1 month), adult (6 month),...

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Détails bibliographiques
Auteurs principaux: Lazarenko, Oxana P., Rzonca, Sylwia O., Hogue, William R., Swain, Frances L., Suva, Larry J., Lecka-Czernik, Beata
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084459/
https://ncbi.nlm.nih.gov/pubmed/17332064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-1587
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