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Tissue Kallikrein Reverses Insulin Resistance and Attenuates Nephropathy in Diabetic Rats by Activation of PI3 kinase/Akt and AMPK Signaling Pathways

We previously reported that intravenous delivery of the human tissue kallikrein (HK) gene reduced blood pressure and plasma insulin levels in fructose-induced hypertensive rats with insulin resistance. In the current study, we evaluated the potential of a recombinant adeno-associated viral vector ex...

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Detalhes bibliográficos
Main Authors: Yuan, Gang, Deng, Juanjuan, Wang, Tao, Zhao, Chunxia, Xu, Xizheng, Wang, Peihua, Voltz, James W., Edin, Matthew L., Xiao, Xiao, Chao, Lee, Chao, Julie, Zhang, Xin A., Zeldin, Darryl C., Wang, Dao Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084357/
https://ncbi.nlm.nih.gov/pubmed/17272402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-0602
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