Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

Disrupted-in-schizophrenia 1 (DISC1) was initially discovered through a balanced translocation (1;11)(q42.1;q14.3) that results in loss of the C terminus of the DISC1 protein, a region that is thought to play an important role in brain development. Here, we use an inducible and reversible transgenic...

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Detalhes bibliográficos
Main Authors: Li, Weidong, Zhou, Yu, Jentsch, J. David, Brown, Robert A. M., Tian, Xiaoli, Ehninger, Dan, Hennah, William, Peltonen, Leena, Lönnqvist, Jouko, Huttunen, Matti O., Kaprio, Jaakko, Trachtenberg, Joshua T., Silva, Alcino J., Cannon, Tyrone D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084334/
https://ncbi.nlm.nih.gov/pubmed/17984054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706900104
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