Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli.

Lysine epsilon-aminotransferase (LAT) in the beta-lactam-producing actinomycetes is considered to be the first step in the antibiotic biosynthetic pathway. Cloning of restriction fragments from Streptomyces clavuligerus, a beta-lactam producer, into Streptomyces lividans, a nonproducer that lacks LA...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Tobin, M B, Kovacevic, S, Madduri, K, Hoskins, J A, Skatrud, P L, Vining, L C, Stuttard, C, Miller, J R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208374/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1917855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.19.6223-6229.1991
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