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Repression by Groucho/TLE/Grg Proteins: Genomic Site Recruitment Generates a Compacted Chromatin Structure in Vitro and Impairs Activator Binding in Vivo
Groucho-related (Gro/TLE/Grg) corepressors meditate embryonic segmentation, dorsal-ventral patterning, neurogenesis, and Notch and Wnt signaling. Although Gro/TLE/Grgs disrupt activator complexes and recruit histone deacetylases (HDAC), activator complexes can be disrupted in various ways, HDAC recr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2083644/ https://ncbi.nlm.nih.gov/pubmed/17964267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.002 |
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