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Effects of dietary management of phenylketonuria on long‐term cognitive outcome

BACKGROUND: Phenylketonuria (PKU) is associated with dopaminergic depletion in the dorsolateral prefrontal cortex and abnormalities of myelination. Both mechanisms may lead to deficits in cognitive functioning. Studies of cognitive outcome in children treated with PKU at an early stage have suggeste...

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Detalhes bibliográficos
Main Authors: Channon, Shelley, Goodman, Galya, Zlotowitz, Sally, Mockler, Caroline, Lee, Philip J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083434/
https://ncbi.nlm.nih.gov/pubmed/17068073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/adc.2006.104786
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