Expression of the 1918 Influenza A Virus PB1-F2 Enhances the Pathogenesis of Viral and Secondary Bacterial Pneumonia

Secondary bacterial pneumonia frequently claimed the lives of victims during the devastating 1918 influenza A virus pandemic. Little is known about the viral factors contributing to the lethality of the 1918 pandemic. Here we show that expression of the viral accessory protein PB1-F2 enhances inflam...

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Bibliographic Details
Main Authors: McAuley, Julie L., Hornung, Felicita, Boyd, Kelli L., Smith, Amber M., McKeon, Raelene, Bennink, Jack, Yewdell, Jonathan W., McCullers, Jonathan A.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083255/
https://ncbi.nlm.nih.gov/pubmed/18005742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2007.09.001
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