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Cyclooxygenase-2 Inhibits UVB-Induced Apoptosis in Mouse Skin by Activating the Prostaglandin E(2) Receptors, EP2 and EP4

Cyclooxygenase-2 (COX-2) is induced by UVB light and reduces UVB-induced epidermal apoptosis; however, the mechanism is unclear. Therefore, wild-type (WT) and COX-2−/− mice were acutely treated with UVB (5 kJ/m(2)), and apoptotic signaling pathways were compared. Following exposure, apoptosis was 2....

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Chun, Kyung-Soo, Akunda, Jacqueline K., Langenbach, Robert
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083120/
https://ncbi.nlm.nih.gov/pubmed/17332329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-3617
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