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An Evolutionary-Network Model Reveals Stratified Interactions in the V3 Loop of the HIV-1 Envelope

The third variable loop (V3) of the human immunodeficiency virus type 1 (HIV-1) envelope is a principal determinant of antibody neutralization and progression to AIDS. Although it is undoubtedly an important target for vaccine research, extensive genetic variation in V3 remains an obstacle to the de...

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Detalhes bibliográficos
Main Authors: Poon, Art F. Y, Lewis, Fraser I, Pond, Sergei L. Kosakovsky, Frost, Simon D. W
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2082504/
https://ncbi.nlm.nih.gov/pubmed/18039027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030231
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