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A Universal Mechanism Ties Genotype to Phenotype in Trinucleotide Diseases
Trinucleotide hereditary diseases such as Huntington disease and Friedreich ataxia are cureless diseases associated with inheriting an abnormally large number of DNA trinucleotide repeats in a gene. The genes associated with different diseases are unrelated and harbor a trinucleotide repeat in diffe...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2082501/ https://ncbi.nlm.nih.gov/pubmed/18039028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030235 |
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