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Tom20 recognizes mitochondrial presequences through dynamic equilibrium among multiple bound states

Most mitochondrial proteins are synthesized in the cytosol and imported into mitochondria. The N-terminal presequences of mitochondrial-precursor proteins contain a diverse consensus motif (φχχφφ, φ is hydrophobic and χ is any amino acid), which is recognized by the Tom20 protein on the mitochondria...

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Hlavní autoři: Saitoh, Takashi, Igura, Mayumi, Obita, Takayuki, Ose, Toyoyuki, Kojima, Rieko, Maenaka, Katsumi, Endo, Toshiya, Kohda, Daisuke
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080804/
https://ncbi.nlm.nih.gov/pubmed/17948058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601888
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