Elevated MMP‐12 protein levels in induced sputum from patients with COPD

BACKGROUND: Several matrix metalloproteinases (MMPs) are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). In mice, MMP‐12 plays a crucial role in the development of cigarette smoke induced emphysema. A study was undertaken to investigate the role of MMP‐12 in the develop...

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Bibliografiska uppgifter
Huvudupphovsmän: Demedts, I K, Morel‐Montero, A, Lebecque, S, Pacheco, Y, Cataldo, D, Joos, G F, Pauwels, R A, Brusselle, G G
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMJ Group 2006
Ämnen:
Chronic Obstructive Pulmonary Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080750/
https://ncbi.nlm.nih.gov/pubmed/16308335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.042432
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