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The RNA binding protein RNPS1 alleviates ASF/SF2 depletion-induced genomic instability
Formation of transcription-induced R-loops poses a critical threat to genomic integrity throughout evolution. We have recently shown that the SR protein ASF/SF2 prevents R-loop formation in vertebrates by cotranscriptionally binding to nascent mRNA precursors to prevent their reassociation with temp...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080599/ https://ncbi.nlm.nih.gov/pubmed/17959926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.734407 |
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