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Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides

Prosaposin, the precursor of saposins A, B, C, and D, was recently identified as a neurotrophic factor. Herein prosaposin was found to increase sulfatide concentrations in primary and transformed Schwann cells (iSC) and oligodendrocytes (differentiated CG4 cells). Of the four mature saposins, only s...

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Détails bibliographiques
Auteurs principaux: Hiraiwa, Masao, Taylor, Eve M., Campana, W. Marie, Darin, Sam J., O’Brien, John S.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences of the USA 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC20801/
https://ncbi.nlm.nih.gov/pubmed/9114068
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