The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates
Valproic acid and lithium are effective antibipolar drugs. We recently showed that lithium stimulated the release of glutamate in monkey and mouse cerebral cortex slices, which, through activation of the N-methyl-d-aspartate receptor, increased accumulation of inositol 1,4,5-trisphosphate [Ins(1,4,5...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9114064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4757 |
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