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The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates

Valproic acid and lithium are effective antibipolar drugs. We recently showed that lithium stimulated the release of glutamate in monkey and mouse cerebral cortex slices, which, through activation of the N-methyl-d-aspartate receptor, increased accumulation of inositol 1,4,5-trisphosphate [Ins(1,4,5...

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Detalles Bibliográficos
Main Authors: Dixon, John F., Hokin, Lowell E.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC20797/
https://ncbi.nlm.nih.gov/pubmed/9114064
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