Cytokine manipulation of primitive human hematopoietic cell self-renewal

Previous studies have shown that primitive human hematopoietic cells detectable as long-term culture-initiating cells (LTC-ICs) and colony-forming cells (CFCs) can be amplified when CD34(+) CD38(−) marrow cells are cultured for 10 days in serum-free medium containing flt3 ligand (FL), Steel factor (...

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Main Authors: Zandstra, P. W., Conneally, E., Petzer, A. L., Piret, J. M., Eaves, C. J.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC20787/
https://ncbi.nlm.nih.gov/pubmed/9114054
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