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Synthesis and antifungal properties of α-methoxy and α-hydroxyl substituted 4-thiatetradecanoic acids

4-Thiatetradecanoic acid exhibited weak antifungal activities against Candida albicans (ATCC 60193), Cryptococcus neoformans (ATCC 66031), and Aspergillus niger (ATCC 16404) (MIC = 4.8-12.7 mM). It has been demonstrated that α-methoxylation efficiently blocks β-oxidation and significantly improve th...

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Detalhes bibliográficos
Main Authors: Carballeira, Néstor M., O’Neill, Rosann, Parang, Keykavous
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2078680/
https://ncbi.nlm.nih.gov/pubmed/17662704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2007.06.218
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