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15-Lipoxygenase-1 Production is Lost in Pancreatic Cancer and Overexpression of the Gene Inhibits Tumor Cell Growth

Pancreatic cancer patients have an abysmal prognosis because of late diagnosis and lack of therapeutic options. Pancreatic intraepithelial neoplasias (PanINs), the precursor lesions, are a potential target for chemoprevention. Targeting eicosanoid pathways is an obvious choice because 5-lipoxygenase...

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Detalhes bibliográficos
Main Authors: Hennig, René, Kehl, Timo, Noor, Seema, Ding, Xian-Zhong, Rao, Sambasiva M, Bergmann, Frank, Fürstenberger, Gerhard, Büchler, Markus W, Friess, Helmut, Krieg, Peter, Adrian, Thomas E
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077883/
https://ncbi.nlm.nih.gov/pubmed/18030360
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