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A Network Analysis of the Human T-Cell Activation Gene Network Identifies Jagged1 as a Therapeutic Target for Autoimmune Diseases

Understanding complex diseases will benefit the recognition of the properties of the gene networks that control biological functions. Here, we set out to model the gene network that controls T-cell activation in humans, which is critical for the development of autoimmune diseases such as Multiple Sc...

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Библиографические подробности
Главные авторы: Palacios, Ricardo, Goni, Joaquin, Martinez-Forero, Ivan, Iranzo, Jaime, Sepulcre, Jorge, Melero, Ignacio, Villoslada, Pablo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077806/
https://ncbi.nlm.nih.gov/pubmed/18030350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001222
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