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Peptide-specific killing of antigen-presenting cells by a recombinant antibody–toxin fusion protein targeted to major histocompatibility complex/peptide class I complexes with T cell receptor-like specificity

Specificity in the immune system is dictated and regulated by specific recognition of peptide/major histocompatibility complex (MHC) complexes by the T cell receptor. Such peptide/MHC complexes are a desirable target for novel approaches in immunotherapy because of their highly restricted fine speci...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Reiter, Yoram, Di Carlo, Angelina, Fugger, Lars, Engberg, Jan, Pastan, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9114042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4631
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