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Switchable DNA interfaces for the highly sensitive detection of label-free DNA targets
We report a method to detect label-free oligonucleotide targets. The conformation of surface-tethered probe nucleic acids is modulated by alternating electric fields, which cause the molecules to extend away from or fold onto the biased surface. Binding (hybridization) of targets to the single-stran...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2077262/ https://ncbi.nlm.nih.gov/pubmed/17951434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703974104 |
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