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Analysis of σ(32) mutants defective in chaperone-mediated feedback control reveals unexpected complexity of the heat shock response

Protein quality control is accomplished by inducing chaperones and proteases in response to an altered cellular folding state. In Escherichia coli, expression of chaperones and proteases is positively regulated by σ(32). Chaperone-mediated negative feedback control of σ(32) activity allows this tran...

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Autores principales: Yura, Takashi, Guisbert, Eric, Poritz, Mark, Lu, Chi Zen, Campbell, Elizabeth, Gross, Carol A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077055/
https://ncbi.nlm.nih.gov/pubmed/17968012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708819104
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