Modulation of Retinoid Signaling by a Cytoplasmic Viral Protein via Sequestration of Sp110b, a Potent Transcriptional Corepressor of Retinoic Acid Receptor, from the Nucleus

Hepatitis C virus (HCV) core protein (core) plays a significant role in the development of chronic liver diseases caused by HCV infection. We have discovered that the core sensitized all-trans-retinoic acid (ATRA)-induced cell death in MCF-7 cells. Activation of retinoic acid receptor alpha (RARα)-m...

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Detalhes bibliográficos
Main Authors: Watashi, Koichi, Hijikata, Makoto, Tagawa, Ayako, Doi, Takahiro, Marusawa, Hiroyuki, Shimotohno, Kunitada
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC207568/
https://ncbi.nlm.nih.gov/pubmed/14559998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7498-7509.2003
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