Retinoic Acid Receptor-Mediated Induction of ABCA1 in Macrophages

ABCA1, the mutant molecule in Tangier Disease, mediates efflux of cellular cholesterol to apoA-I and is induced by liver X receptor (LXR)/retinoid X receptor (RXR) transcription factors. Retinoic acid receptor (RAR) activators (all-trans-retinoic acid [ATRA] and TTNPB) were found to increase ATP-bin...

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Detalhes bibliográficos
Main Authors: Costet, Philippe, Lalanne, Florent, Gerbod-Giannone, Marie C., Molina, Jennifer R., Fu, Xuan, Lund, Erik G., Gudas, Lorraine J., Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC207565/
https://ncbi.nlm.nih.gov/pubmed/14560020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7756-7766.2003
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