Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways

The burden of type 2 diabetes and its associated premature morbidity and mortality is rapidly growing, and the need for novel efficacious treatments is pressing. We report here that serotonin 2C receptor (5-HT(2C)R) agonists, typically investigated for their anorectic properties, significantly impro...

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Autors principals: Zhou, Ligang, Sutton, Gregory M., Rochford, Justin J., Semple, Robert K., Lam, Daniel D., Oksanen, Laura J., Thornton-Jones, Zoe D., Clifton, Peter G., Yueh, Chen-Yu, Evans, Mark L., McCrimmon, Rory J., Elmquist, Joel K., Butler, Andrew A., Heisler, Lora K.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2007
Matèries:
Short Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075535/
https://ncbi.nlm.nih.gov/pubmed/17983585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.10.008
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