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Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

In efforts to develop an effective vaccine, sterilizing immunity to primate lentiviruses has only been achieved by the use of live attenuated viruses carrying major deletions in nef and other accessory genes. Although live attenuated HIV vaccines are unlikely to be developed due to a myriad of safet...

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Bibliografski detalji
Glavni autori: Gorry, Paul R, McPhee, Dale A, Verity, Erin, Dyer, Wayne B, Wesselingh, Steven L, Learmont, Jennifer, Sullivan, John S, Roche, Michael, Zaunders, John J, Gabuzda, Dana, Crowe, Suzanne M, Mills, John, Lewin, Sharon R, Brew, Bruce J, Cunningham, Anthony L, Churchill, Melissa J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075523/
https://ncbi.nlm.nih.gov/pubmed/17888184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-66
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