Menaquinone (vitamin K2) biosynthesis: evidence that the Escherichia coli menD gene encodes both 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase and alpha-ketoglutarate decarboxylase activities.

The formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid (SHCHC), the first identified intermediate in the menaquinone biosynthetic pathway, requires two reactions. They are the decarboxylation of alpha-ketoglutarate by an alpha-ketoglutarate decarboxylase, which results in the for...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Palaniappan, C, Sharma, V, Hudspeth, M E, Meganathan, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1459959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.24.8111-8118.1992
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