Downregulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system

BACKGROUND: Matrix metalloproteinases (MMPs) are thought to mediate cellular infiltration in central nervous system (CNS) inflammation by cleaving extracellular matrix proteins associated with the blood-brain barrier. The family of MMPs includes 23 proteinases, including six membrane type-MMPs (MT-M...

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Bibliographische Detailangaben
Hauptverfasser: Toft-Hansen, Henrik, Babcock, Alicia A, Millward, Jason M, Owens, Trevor
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075488/
https://ncbi.nlm.nih.gov/pubmed/17883829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-24
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