Loss of caveolin-3 induced by the dystrophy-associated P104L mutation impairs L-type calcium channel function in mouse skeletal muscle cells

Caveolins are membrane scaffolding proteins that associate with and regulate a variety of signalling proteins, including ion channels. A deficiency in caveolin-3 (Cav-3), the major striated muscle isoform, is responsible for skeletal muscle disorders, such as limb-girdle muscular dystrophy 1C (LGMD...

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Hlavní autoři: Couchoux, Harold, Allard, Bruno, Legrand, Claude, Jacquemond, Vincent, Berthier, Christine
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2007
Témata:
Cellular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075458/
https://ncbi.nlm.nih.gov/pubmed/17317753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.124198
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