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Inflammation reduces the contribution of N-type calcium channels to primary afferent synaptic transmission onto NK1 receptor-positive lamina I neurons in the rat dorsal horn

N-type calcium channels contribute to the release of glutamate from primary afferent terminals synapsing onto nocisponsive neurons in the dorsal horn of the spinal cord, but little is known of functional adaptations to these channels in persistent pain states. Subtype-selective conotoxins and other...

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Autori principali: Rycroft, Beth K, Vikman, Kristina S, Christie, MacDonald J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075448/
https://ncbi.nlm.nih.gov/pubmed/17303639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-1-02117.x
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